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盐酸替扎尼定片可以治疗哪些疾病

发布时间2022-03-06 00:29:23  来源:粤迅康
【导读】盐酸替扎尼定片可以治疗什么疾病呢?:盐酸替扎尼定片为中枢性α2肾上腺素受体激动剂,盐酸替扎尼定片可能是通过增强运动神经元的突触前抑制作用而降低强直性痉挛状态。
盐酸替扎尼定片(凯莱通) ¥ 37.00元

规格:2mg*24s

作用:(1) 下列疾病造成的疼痛性肌痉挛的改善-颈、肩及腰部疼痛等局部疼痛综合征。 (2) 下列疾病引起的中枢性肌强直-脑血管意外、手术后遗症(脊髓损伤、大脑损伤)、脊髓小脑变性、多发性硬化症、肌萎缩性侧索硬化症等。

盐酸替扎尼定片的主要成分是盐酸替扎尼定,其化学名称是5-氯-4-(2-咪唑啉-2-氨基)-2,1,3-苯硫噻嗪盐酸盐。那么,盐酸替扎尼定片可以治疗哪些疾病呢?

盐酸替扎尼定片(凯莱通)

盐酸替扎尼定片是中枢性的α2对于肾上腺素受体激动剂,盐酸替扎尼定片可以通过增强运动神经元的突触前抑制来减少强直性痉挛。动物实验表明,盐酸替扎尼定片对骨骼肌纤维和神经肌接头无直接作用,对单突触脊髓反射较弱。盐酸替扎尼定片对多突触通路的作用最强,与脊髓运动神经元易化性降低有关。

盐酸替扎尼定片口服吸收良好,其绝对口服生物利用率为40%(变异系数CV=24%)。口服后达峰浓度的时间为1.5h(CV=40%)。食物可以使口服药物后药浓度达到峰值(Cmax)增加近1/3,缩短达峰时间40min,但不影响胃肠道对药物的总吸收。盐酸替扎尼定片可治疗以下疾病:

1、颈肩腰痛等局部疼痛征(如颈椎病、肩周炎、椎间盘突出等)引起的外周肌肉疼痛;

盐酸替扎尼定片(凯莱通)

2、各种慢性头痛,尤其是慢性紧张性头痛;

3、中枢损伤引起的强直性痉挛(如脑血管事故、手术后遗症、脊髓小脑变性、多发性硬化、肌萎缩性侧索硬化等。

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